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3 Best Supplements for Dogs: Heart, Kidney & Liver Support Every Pet Parent Should Know

Most dogs don't need a cabinet full of supplements. What they need is targeted, science-backed support for the organs that carry the most load as they age: the heart, the kidneys, and the liver.

3 Best Supplements for Dogs
3 Best Supplements for Dogs

These three organs work together to filter waste, circulate blood, and regulate metabolism. When even one begins to struggle, the effects ripple outward — reduced energy, slower recovery, and a declining quality of life.


Here are the 3 best supplements for dogs based on where the greatest clinical need exists — each formulated by RX Sciences under veterinary guidance.


1. HeartRX — Cardiac Support for Dogs

Heart disease affects an estimated 10% of all dogs seen in veterinary practice, with numbers rising sharply in seniors and small breeds like Cavalier King Charles Spaniels, Dachshunds, and Chihuahuas. Larger breeds such as Dobermans and Boxers face elevated risk of Dilated Cardiomyopathy (DCM).

HeartRx™ 2.5mg
MYR 0.00
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HeartRX is formulated around Pimobendan — a clinically proven cardiac compound that works as both a positive inotrope (strengthens heart contractions) and a vasodilator (reduces heart workload). It is commonly used to support dogs with:

  • Mitral Valve Disease (MVD)

  • Dilated Cardiomyopathy (DCM)

  • Early-stage and active Congestive Heart Failure (CHF)


Available in 1.25 mg and 5 mg coated tablets, dosed at 0.25 mg/kg twice daily under veterinary supervision.


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2. KidneyRX — Renal Support for Dogs

Kidney decline in dogs is often silent until a significant portion of function has already been lost. Chronic Kidney Disease (CKD) is one of the leading causes of illness in senior dogs — and it progresses slowly, which is why proactive nutritional support matters.

KidneyRx™ – Effective Kidney Solution for Cats and Dogs
MYR 199.00
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KidneyRX is a veterinary-formulated kidney support supplement designed for long-term daily use. It is commonly recommended for dogs with:

  • Chronic Kidney Disease (CKD) at any stage

  • Recurrent urinary tract infections or kidney stones

  • Early kidney decline with proteinuria

  • Metabolic or inflammatory renal stress


Purpose-driven ingredients, flexible weight-based dosing, and a formulation built for consistency make it a practical choice for ongoing kidney management alongside diet and veterinary monitoring.


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3. LiverRX — Hepatic Support for Dogs

The liver metabolises nutrients, detoxifies the blood, produces bile, and anchors the body's antioxidant defence. Dogs on long-term medications (NSAIDs, steroids, anticonvulsants), seniors, and those recovering from illness are all at elevated risk for hepatic stress.

LiverRx™ for Dogs
MYR 189.00
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LiverRX for Dogs is built around four clinically respected ingredients:

  • SAMe — supports liver metabolism and glutathione production

  • Silybin A+B (Milk Thistle) — protects and supports liver cell regeneration

  • Vitamin E — fat-soluble antioxidant for cellular protection

  • Vitamin C — water-soluble antioxidant supporting detoxification


It is commonly used for dogs with elevated liver enzymes, drug-induced hepatic stress, recovery from liver illness, and long-term senior liver maintenance.


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The Right Supplement Starts with the Right Diagnosis

Before starting any supplement, consult your veterinarian to confirm which organs need support, determine the correct dose, and ensure compatibility with existing medications. RX Sciences' three-product range — HeartRX, KidneyRX, and LiverRX — is designed to work as a coherent organ support system when used under professional guidance.



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